A 36-year-old patient presents to the clinic with a four-month symptoms that lead to a diagnosis of major depressive disorder. She reports no significant past medical history and has no known drug allergies. Her family history is non-contributory. This is her first time seeking treatment for these symptoms. Considering her clinical presentation and history, what is the most appropriate initial pharmacological treatment for her diagnosed major depressive disorder? oxycodone, ibuprofen, celecoxib, flexeri