GI is a 45 yo woman coming to clinic today complaining of sensations of warmth that start in her stomach and go up to her throat. It happens after dinner, especially if she eats right before bed and occurred five times in the past week. The symptoms impact her quality of life. She denies throat pain, chest pain, or difficulty swallowing. Based on GI’s symptoms, what is the most appropriate initial therapy to recommend for suspected GERD? GI is a 45 yo woman coming to clinic today complaining of sensations of warmth that start in her stomach and go up to her throat. It happens after dinner, especially if she eats right before bed and occurred five times in the past week. The symptoms impact her quality of life. She denies throat pain, chest pain, or difficulty swallowing. Based on GI’s symptoms, what is the most appropriate initial therapy to recommend for suspected GERD? Proton pump inhibitor daily plus histamine-2 receptor antagonist at bedtime Proton pump inhibitor once daily Lifestyle modifications plus prokinetics as needed Lifestyle modifications onlyGI is a 45 yo woman coming to clinic today complaining of sensations of warmth that start in her stomach and go up