A 32-year-old woman is seen for a follow-up visit with her primary care medical provider for management

    May 5, 2024

A 32-year-old woman is seen for a follow-up visit with her primary care medical provider for management of recently diagnosed genital herpes. Routine screening laboratory studies show a negative HIV-1/2 antigen-antibody test, a negative hepatitis B surface antigen (HBsAg), a positive anti-HCV, and a positive HCV RNA. When given the results, she discloses a brief period of injection drug use about 10 years prior. She is told by her provider that she has chronic hepatitis C virus (HCV) infection. She is currently asymptomatic and wants to know how likely it is that she goes on to develop liver cirrhosis. Without treatment, approximately what percentage of persons with untreated chronic hepatitis C virus (HCV) infection go on to develop cirrhosis after 20 to 30 years? 1% 5% 15% 55%

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