A 22-year-old woman presents to the clinic with periorbital and forehead swelling and intensely pruritic, erythematous wheals on her face and chest. She says the symptoms began 4 hours ago, approximately 45 minutes after taking ibuprofen for a headache. She reports no other symptoms. Her airway is patent, and her vital signs are within normal limits. Which of the following is the most appropriate pharmacologic therapy for this patient? Cetirizine 10 mg tablets twice daily and diphenhydramine 50 mg at bedtime Epinephrine IM injection administered immediately in the anterolateral aspect of the middle one-third of the thigh Hydrocortisone 1% cream applied topically twice daily to affected areas Prednisone 40 mg once daily for 5 days