Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories. For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
To Prepare:
Review the case study posted in “Announcements” by your Instructor for this Assignment
Review the information provided and answer questions posed in the case study
When recommending a medication, write out a complete prescription for the medication

Whenever possible, use clinical practice guidelines in developing your answers when possible
Include at least three references to support your answer and cite them in APA format.
Directions: For each of the scenarios below, answer the questions below using clinicalpractice guideline where applicable. Explain the problem and explain how you wouldaddress the problem. If prescribing a new drug, write out a complete medication orderjust as you would if you were completing a prescription. Use at least 3 sources for eachscenario and cite sources using APA format.
1. A 52-year-old man was recently discharged from the hospital following treatment foratrial fibrillation. He was discharged on Warfarin 5 mg po q day and Amiodarone 200mg tid. His INR is 8.8. What interaction has occurred with these 2 medications?What changes in his medications would you make?
2. A 44-year-old women is currently taking Glipizide and Phenytoin. She has a newprescription for Ceftriaxone. All three medications are known to be highly proteinbound. What effect does protein binding have on drug availability? How would youmanage this patient’s medication?

3. Name two drugs that are highly affected by the first pass effect. As a prescriber,what actions would you take in prescribing these drugs to counter the first passeffect?
4. James is a 49-year-old male that was prescribed atenolol for his high bloodpressure. James states that he only occasionally takes the medication because hedoes not like the side effects. What information would you provide to the patient athis visit? How would you manage his medication?