Dion is a 59-year-old-male with severe OA and T2DM. He is currently taking tramadol 100 mg QID PRN, which helps his pain to a degree, but continues to experience neuropathic pain, which limits his ability to work. You’d like to start him on gabapentin. What is important to consider prior to Dion starting gabapentin? A: Gabapentin will make his neuropathic pain worse before it gets better B: Gabapentin will reduce the effects of tramadol C: Gabapentin has no effect on tramadol D: Gabapentin has limited abuse potential, unlike tramadol E: Gabapentin can potentiate the effects of tramadol