Please write the initial discussion post on the following (Hyperlinks to resources are include below):
Explain the importance of systematic review and meta-analysis for evidence-based practice.

What are the limitations of the systematic review?
How does one overcome the challenges?
Offer an example of a situation where systematic review and meta-analysis were one of the defining points in the decision-making process, and when without it the decision might have been incorrect. 
Qualitative Analysis in Health Services Research, Part 2
Cochrane Handbook for Systematic Review of Interventions
Methodology in Conducting a Systematic Review
Five Steps to Conducting a Systematic Review