(P) In adult patients diagnosed with type 2 diabetes (I) does the implementation of a structured exercise program (C) compared to standard care without structured exercise (O) result in a significant reduction in HbA1c levels over a 6-month period? Research Purpose: The research purpose that best fits this PICO question is likely to be explanatory or interventional. This is because the study aims to investigate the effectiveness of a specific intervention (structured exercise program) on a particular outcome (reduction in HbA1c levels) among a specific population (adults with type 2 diabetes). Significance to Nursing: This PICO question is significant to nursing as it addresses a crucial aspect of diabetes management, which is a prevalent chronic condition. Understanding the impact of a structured exercise program on HbA1c levels can contribute to evidence-based practice in nursing, informing healthcare providers about the potential benefits of incorporating structured exercise interventions into the care plans for patients with type 2 diabetes. This knowledge can guide nursing interventions, improve patient outcomes, and enhance the overall quality of diabetes care. Reference Polit, D.F.