Your patient Marla has come to you concerned about her continued knee pain. She has tried aquatic therapy, but walking has been difficult for her. She is willing to wear a tibiofemoral knee brace but also wants to know if you will prescribe the topical NSAID (nonsteroidal anti-inflammatory drug) her friend told her about. What is your next step to determine if this is an appropriate treatment regimen? Review Marla’s medical history for risk factors for coronary artery disease, angina, or stroke Perform a pregnancy test to rule out early pregnancy Ask Marla if she has a history of depression or anxiety Determine if Marla has a history of irritable bowel syndrome